Autophagy, Intermittent Fasting, and Fasting Mimicking


Away we go!

Autophagy

The physiological benefits of fasting include anti-aging (and even anti-cancer) activity by turning on a process in the body called “autophagy,” which triggers the body to “clean up.” In this process, our cells remove damaged contents so they can be metabolized and excreted from the body.

Autophagy is a natural way to get pathogens and abnormal contents in cells out of the body. Autophagy provides anti-aging benefits and potentially even some anti-cancer benefits, because when cells act abnormally and replicate in an uncontrolled manner, that’s essentially how cancer develops. Autophagy removes these abnormal or damaged cells before they get out of hand.

So, fasting turns on autophagy and the fasting mimicking diet seeks to engage that process without having to stop eating completely. In short, you still eat food but calories are limited (800-1100 calories per day), and in theory you still get the benefits of fasting.

Fasting Mimicking Trials

The outcomes of the first small scale human trials of Fasting Mimicking Diets or FMD are reported by Dr. Valter Longo as including:

  • Reduction in blood glucose and large increase in ketones
  • 25%+ reduction in circulating Insulin Growth Factor-1 (IGF-1)
  • Reduction in C-Reactive Protein (CRP)
  • Positive changes in cholesterol and triglyceride levels
  • Reduction in body weight
  • Improvement and rejuvenation of the immune system
  • Activation of autophagy



“Old keys will never open new doors.”

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